The Hollywood Reporter writes that John Cusack has replaced Christian Slater as the voice of the title character in Exodus Film Group’s Igor. Concurrently, Sean Hayes has taken the role of Brian the Brain, described as “a brain in a jar who is one of Igor’s sidekicks and inventions.” The duo join a cast that includes Jeremy Piven, Jay Leno, Jennifer Coolidge, Molly Shannon, Steve Buscemi and John Cleese.