With an estimated opening of $70 million from 3,103 locations, 300 looks to dethrone Ice Age: The Meltdown as having the highest-grossing first weekend in March. Debuting March 31, 2006, Meltdown took in approximately $68,033,544, with an average of $17,163 throughout its nearly 4,000 theaters. By contrast, 300 appears to have averaged $22,567 in each of its 3,103 theaters, according to Box Office Guru.